Antimicrobial agents – optimising the ecological balance
نویسندگان
چکیده
منابع مشابه
Antimicrobial agents – optimising the ecological balance
BACKGROUND There is no more challenging a group of pharmaceuticals than antimicrobials. With the antibiotic era came great optimism as countless deaths were prevented from what were previously fatal conditions. Although antimicrobial resistance was quickly identified, the abundance of antibiotics entering the market helped cement attitudes of arrogance as the "battle against pestilence appeared...
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Emergence of resistance by bacterial and fungal stains towards existing antimicrobial agents is one of the major problem as well as motivation to synthesize a new class of antimicrobial agents possessing potent activity compared to commonly used therapy. Coumarin is the heterocyclic compound formed from benzene and pyrone ring containing oxygen and its derivatives are of wide awareness because ...
متن کاملAntimicrobial Agents
Use of substances with antimicrobial properties is known to have been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. More recently, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism for some bacteria and discussed the merits of controlling these interactions in medicine. ...
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INTRODUCTION................................................................. 13 PRECLINICAL TESTING STAGES ................................................................. 13 Discovery of New Antibiotics ................................................................. 13 Establishment of SAR ................................................................. 15 Animal Models for Studying the P...
متن کاملAntimicrobial agents.
The pharmacokinetics of apalcillin and piperacillin, each administered intravenously as a single 2-g dose, were compared in 10 volunteers in a randomized study of crossover design using bioassay and high-pressure liquid chromatographic procedures. The concentrations of both penicillins in serum were determined over a period of 12 h and in urine over 24 h. Concentrations of apalcillin and pipera...
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ژورنال
عنوان ژورنال: BMC Medicine
سال: 2016
ISSN: 1741-7015
DOI: 10.1186/s12916-016-0661-z